CBBM Lecture "Nuclear Reorganisations Controlling Sleep and Metabolism" by

Prof. Steven A. Brown,

Chronobiology and Sleep Research Group,

Institute of Pharmacology and Toxicology,

University of Zurich,


will take place on Tuesday, April 24, 2018 from 17:15 to 18:15 hours in CBBM, Ground Floor, B1/B2.

Host: Prof. Henrik Oster
Institute of Neurobiology
University of Lübeck


After undergraduate research in yeast genetics and graduate studies on chromatin biochemistry at Harvard, Steven Brown moved to Geneva for postdoctoral work, where he first began to study biological clocks and sleep in the laboratory of Ueli Schibler.  Following a stay at Charité Universitätsmedezin as a Humboldt fellow, he returned to Switzerland in 2007 as an assistant professor and then professor.  His laboratory studies the molecular mechanisms and neural circuits underlying sleep and diurnal behaviour, using human cells and mouse models.  His studies of human cells recently culminated in cellular GWAS studies to show how common regulatory variation affects human daily behavior; and his mouse studies have led to the discovery of novel causes of human intellectual disability and clock plasticity. His team has also pioneered the use of metabolomics to study circadian function, including in exhaled breath.