Zur Navigation springenZum Content springenLogin | Contact | Legal Notice | Data Protection
Logo
  • GRK 1957
    • Organization
    • Office
    • MD Stipends
  • People
    • Doctoral Researchers
    • Postdoctoral Researchers
    • Medical Students
    • Exchange Students
    • Participating Researchers
    • Staff
    • Alumni
  • Research
    • 1st Generation Projects
    • 2nd Generation Projects
    • 3rd Generation Projects
    • International Partners
  • Publications
  • Training
    • Scientific Seminars
    • ABC-Lectures Series
    • Summer Schools and Retreats
    • Symposium 2017
    • Symposium 2019
    • Symposium 2022
    • ABC Final Meeting 2023
    • Complementary Courses
    • Gender Equality
  • News
    • Archive
GRK1957 | Adipocyte-Brain Crosstalk
University of Lübeck - GRK1957 - GRK 1957

Welcome at the GRK1957 "Adipocyte-Brain Crosstalk"

Our DFG funded Graduiertenkolleg 1957 offers focused research projects and a structured training programme. In an interdisciplinary research approach we address the effects of hormones derived from adipose tissue (adipokines) on CNS function and, in turn, the control of adipose tissue and body weight by the brain. 

Welcome at the GRK1957 "Adipocyte-Brain Crosstalk"

Adipokine research

Adipocytes secrete bioactive factors that act in an autocrine, paracrine, or endocrine manner similar to the cytokine peptides of the immune system, thus termed adipokines. Since the discovery of the first adipokine, leptin, a growing number of such fat cell-derived peptide hormones has been described including adiponectin, nesfatin-1, or visfatin; but also inflammatory cytokines and steroid hormones. 
At the Lübeck campus a unique and historically grown focus on adipokine research exists with a strong integration of basic and clinical research. 

dipokine research

Central adipokine effects

Adipokines signal the adipose state to appetite-regulating centres of the brain. In the hypothalamus, leptin inhibits appetite-promoting neurons in the arcuate nucleus and promotes energy expenditure via stimulation of sympathetic nerve activity to adipose tissues. Such feedback mechanisms also exist for other adipokines. The complex autoregulatory feedback system between central and adipose tissues is essentially involved in adjusting setpoints of energy homeostasis.
This adipocyte-brain crosstalk (ABC) lies at the heart of our DFG research training group GRK 1957.

Central adipokine effects

GRK 1957

Organization
People
Jobs

Research

Projects
International Partners
Publications

Training

Scientific Seminars
ABC-Lecture Series
Summer Schools


Data protection

This video is played via YouTube - ony if you click below, data from you will be sent to YouTube.

By clicking on "Unlock video", personal data such as your IP address and your browser type are transmitted to the servers of YouTube (Google). This is necessary for playing the video. You can withdraw this consent by closing the window of your browser at any time with effect for the future, but you will no longer be able to play the video. By clicking on the "Unlock video" box below, you consent to the transmission of this data to an insecure third country (USA) where there is no adequate level of data protection (Art. 49 Abs 1 lit a DSGVO).

For more information on data protection, please see our privacy policy.

Unlock Video

News

No news available.

GRK 1957
Phone: +49 451 3101 4303
E-Mail: chaoqun.jiang(at)uni-luebeck.de